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Stephan Meister


Research Interests

The role of PGRP proteins in innate immunity pathways in the malaria vector Anopheles gambiae.

The Anopheles gambiae peptidoglycan recognition protein (PGRP) gene family consists of 7 genes with 13 PGRP domains. We analyze the role of these genes in the mosquito immune defense to bacteria and the malaria parasite Plasmodium berghei. We have previously shown that the NF-κB transcription factor REL2 is involved in defense against both types of bacteria and malaria parasites [1]. IMD is only responsible for the reaction against Gram-positive bacteria and Plasmodium. Our data suggests significant divergence as well as many similarities of immune signaling between Anopheles gambiae and the fruit fly Drosophila melanogaster. The differences most likely reflect the different lifestyles of the two insects and, consequently, different infectious agents that the two insects encounter during their lifetimes. In mosquitoes, one of these agents is the malaria parasite Plasmodium.

Conference posters

BioMalPar Conference, Heidelberg, Germany, 2006
BioMalPar Conference, Heidelberg, Germany, 2006
BDV Course, Colorado, USA 2004
BDV Course, Colorado, USA 2004
EMBO PRR Workshop, Trest by Prague 2003
EMBO PRR Workshop, Trest by Prague 2003


Error fetching PMID 16076953:
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  1. Error fetching PMID 16076953: [meister2005]
  2. Meister S, PhD Thesis, EMBL/University of Heidelberg, 2006.


  3. Error fetching PMID 15582524: [meister2004]
  4. Error fetching PMID 14623973: [kumar2003]
  5. Error fetching PMID 12364793: [christoph2002]
  6. Error fetching PMID 12364791: [holt2002]
  7. Error fetching PMID 12077297: [dimopoulos2002]
  8. Error fetching PMID 11516643: [dunipace2001]
  9. Meister S, Diploma Thesis, University of Wuerzburg, 2001.


All Medline abstracts: PubMed HubMed